Production de vaccins humains

 

 

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history of human vaccine production

The vaccine from the Institut Pasteur in Dakar has been the most recent product for 30 years, it is called a“ French neurotropic vaccine ”or“ Dakar vaccine ”. This is a live vaccine attenuated by human mouse brain virus viruses. In 1932, was carried out with a modified French subcutaneous route without the addition of serum.

This stable vaccine, perfectly adapted to the conditions of mass vaccination, has been used to treat cases of epidemic disease in Africa. From 1937 to 1983, nearly 192 million doses were updated by the Institut Pasteur in Dakar, first on the brains of mice, from 1966, on chicken embryos.

The development of a stable and better treated vaccine from the 17D Rockefeller source (strain isolated in 1927 in Ghana) was supplanted by" Dakar vaccine "in 1983 following the work of Pr BARME of the Institut Pasteur in Paris, which improved the thermostability of the vaccine and a new donation.

In preparation for an artisanal preparation in 1966, the production rose to a recognized industrial level.