Institut pasteur de Dakar
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Dr DIEYE Yakhya

Head of the Microbiology Department

Tel : +221-338399241

 

Training

  • 2002: PhD in Cellular and Molecular Genetics, Paris-Sud University, Orsay, France. Thesis title: “Targeting of heterologous proteins in lactic acid bacteria: towards the use of Lactococcus lactis as a vehicle for useful molecules in the digestive tract of the host”.
  • 1998: Diploma of Advanced Study in Cellular and Molecular Genetics, Paris-Sud University, Orsay, France.
  • 1997: Master's degree in Cellular and Molecular Genetics, Paris-Sud University, Orsay, France.
  • 1996: Bachelor of Biochemistry, Paris-Sud University, Orsay, France.
  • 1987: University Diploma of Technology (DUT) in Biological Analysis, Higher National University of Technology, Dakar, Senegal.

 

Professionnal career

  • Since 2015: Associate Professor

Department of Chemical Engineering and Applied Biology, École Supérieure Polytechnique (ESP), University Cheikh Anta Diop (UCAD) Dakar, Senegal

  • 2013-2015: Visiting Senior Research Fellow

Marshall Centre, High Impact Research, University of Malaya,

Kuala Lumpur 50603, Malaysia.

  • 2008-2013: Senior Scientist

Ondek Pty Ltd, Marshall Biotechnology Centre for Infectious Diseases Research and Training,

University of Western Australia, Nedlands, WA 6009.

  • 2005-2008: Postdoctoral Research Associate

The Biodesign Institute, Arizona State University,

1001 South McAllister Avenue Tempe, AZ  85287

  • 2002-2005: Postdoctoral Researcher

The Ohio State University, Department of Microbiology

484 West 12th Avenue Columbus, OH  43210 USA.

  • 1988-1995: Senior technician

Institut Pasteur, Laboratory of Immunology, 36 Avenue Pasteur, Dakar, Senegal.

 

Research activities

  • Pathogenesis of Salmonella
  • Genetics of antimicrobial resistance
  • Microbimoma and infectious and non-communicable diseases

 

Public Health Activities

  • External Assessment of Antimicrobial Resistance (AMR)
  • "One Health of RAM" monitoring

 

Training activities

  • Microbial genetics, training of design engineers
  • Genetic engineering, training of design engineers
  • Molecular biology, DUT training and Professional license
  • Formal genetics, DUT training

 

Major publications

  • Smith SI, Ajayi A, Jolaiya T, Onyekwere C, Setshedi M, Schulz C, Otegbayo JA, Ndip R, Dieye Y, Alboraie M, Ally R, Gunturu R, Hyasinta J, Ugiagbe R, Ndububa D, Arigbabu A; African Helicobacter and Microbiota Study Group. Helicobacter pylori infection in Africa: update of the current situation and challenges. Digestive Diseases. 2021 Aug 11. doi: 10.1159/000518959. 
  • Lazarus DD, Afolayan FID, Mamo G, Dinga JN, Akinbobola J, Duedu KO, Tshifhiwa N, Kassa T, Nene V, Dieye Y, and M Oumouna. 2020. African Vaccinology Network (AfVANET): an African network by African scientists. Pan African Medical Journal 37:66.
  • Dieye Y, Mbengue B, Dagamajalu S, Fall MM, Loke MF, Nguer CM, Thiam A, Vadivelu J, and A Dieye. 2016. Cytokine response during non-cerebral and cerebral malaria: evidence of a failure to control inflammation as a cause of death in African adults. PeerJ 4:e1965.
  • Khosravi Y, Dieye Y, Loke MF, Goh KL, J Vadivelu. 2014. Streptococcus mitis induces conversion of Helicobacter pylori to coccoid cells during co-culture in vitro. PLoS One 9 (11):e112214.
  • Khosravi Y, Dieye Y, Poh BH, Ng CG, Loke MF, Goh KL, J Vadivelu. 2014. Culturable Bacterial Microbiota of the Stomach of Helicobacter pylori-positive and negative gastric disease patients. Scientific World Journal 2014:610421.
  • Ali MM, Newsom DL, González JF, Sabag-Daigle A, Stahl C, Steidley B, Dubena J, Dyszel JL, Smith JN, Dieye Y, Arsenescu R, Boyaka PN, Krakowka S, Romeo T, Behrman EJ, White P, and BMM Ahmer. 2014. Fructose-asparagine is a primary nutrient during growth of Salmonella in the inflamed intestine. PLoS Pathogens 10(6):e1004209.
  • Oxaran V, Ledue-Clier F, Dieye Y, Herry JM, Péchoux C, Meylheuc T, Briandet R, Juillard V, and JC Piard. 2012. Pilus biogenesis in Lactococcus lactis: molecular characterization and role in aggregation and biofilm formation. PLoS One 7 (12):e50989.
  • Dieye Y, Oxaran V, Ledue-Clier F, Alkhalaf W, Buist G, Juillard V, Lee CW, and JC Piard. 2010. Functionality of Sortase A in Lactococcus lactis. Applied and Environmental Microbiology 76 (21):7332-7.
  • Dieye Y, Ameiss K, Mellata M, and R Curtiss III. 2009. The Salmonella Pathogenicity Island (SPI) 1 contributes more than SPI2 to the colonization of the chicken by Salmonella enterica serovar Typhimurium. BMC Microbiology 9:3.
  • Dieye Y, Dyszel J, Kader R, and BM Ahmer. 2007. Systematic analysis of the regulation of type three secreted effectors in Salmonella enterica serovar Typhimurium. BMC Microbiology 7:3.
  • Dieye Y, Hoekman AJ, Clier F, Juillard V, Boot HJ, and JC Piard. 2003. Ability of Lactococcus lactis to export viral capsid antigens: a crucial step for development of live vaccines. Applied and Environmental Microbiology. 69 (12):7281-8.
  • Dieye Y, Usaï S, Clier F, Gruss A, and JC Piard. 2001. Design of a protein targeting system for lactic acid bacteria. Journal of Bacteriology. 183:4157-4166.

Yakhya DIEYE

Head of the Microbiology Department